Lena
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Joined: 21 Apr 2007
Posts: 100
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Brain structure changes occur years before a person shows signs of memory loss caused by Alzheimer's disease or other forms of dementia, a new U.S. study suggests.
The study, published in the April 17 issue of the journal Neurology, included 136 healthy people over the age of 65 who underwent brain scans and cognitive tests at the start of the study and were all found to be cognitively normal. They were then assessed once a year for five years.
By the end of the five years, 23 participants had developed mild cognitive impairment (MCI), and nine of those 23 people were later diagnosed with Alzheimer's disease.
The brain scans revealed that the 23 who developed MCI or Alzheimer's had less gray matter in key memory processing areas of their brains at the beginning of the study. Those 23 people also scored lower on cognitive tests at the start of the study, although their scores were within the normal range.
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